Journal article

Recent developments in radiolabelled peptides for PET imaging of cancer

CL Charron, AL Farnsworth, PD Roselt, RJ Hicks, CA Hutton

Tetrahedron Letters | PERGAMON-ELSEVIER SCIENCE LTD | Published : 2016

DOI: 10.1016/j.tetlet.2016.07.083

Abstract

This digest highlights recent developments in the field of molecular imaging of cancer using peptide-based targeting entities. Syntheses of novel radiolabelled prosthetic groups and new radiolabelled peptide conjugates are highlighted. This review focuses on developments made using positron emission tomography isotopes such as fluorine-18, carbon-11, gallium-68 and copper-64 within the last 5 years.

University of Melbourne Researchers

Peter Roselt Author

Craig Hutton Author

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Grants

Awarded by Australian Research Council

Funding Acknowledgements

Financial support from the Australian Research Council (DP120101454, DP150100692) is gratefully acknowledged.

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17Web of Science

Keywords

Heterodimeric Peptide

In-Vivo Evaluation

Bradykinin B1 Receptor

3405 Organic Chemistry

Chemistry, Organic

Prostate-Cancer

Biomedical Imaging

34 Chemical Sciences

Molecular Imaging

Preclinical Evaluation

Bombesin Analogs

Biological Evaluation

Positron-Emission-Tomography

3404 Medicinal and Biomolecular Chemistry

Cd13 Receptor Expression

Physical Sciences

Science & Technology

Bifunctional Chelator